医院药品不良反应快速上报信息化系统应用效果研究

Study on the Application Effects of ADR Rapid Reporting System in the Hospital

目的:提高医院药品不良反应(ADR)上报质量。方法:采用医院集中监测模式,收集医院ADR快速上报信息系统应用前后的ADR报告表,对上报数量、报告类型、时限及质量等进行统计分析。结果:系统应用后可实现快速上报功能,系统应用前后,上报总数由589份上升至748份,所有严重的ADR比例由6.28%提高到11.76%,报告质量评分由93.64分上升到98.36分,不超时报告占比由94.05%提高到97.33%,差异均有统计学意义(P<0.05)。结论:医院ADR快速上报信息化系统有利于提高报告效率、保证报表质量、扩大监测网络覆盖面,可为药品安全科学评价和监管奠定基础。

OBJECTIVE： To improve the quality of ADR reports. METHODS： By using intensive hospital monitoring mode, ADR reports before and after the application of the system would be collected and factors as report quantity, type, time and quality of reports were analyzed statistically. RESULTS： It provided rapid reporting function after the implementotion of the system. Total quantity of reported ADR cases increased from 589 to 748, and the proportion of all the serious ADR reports increased from 62.8% to 11.76%. The score of repert quality increased from 93.64 to 98.36, the proportion of time-out reports increased from 94.05% to 97.33%, with statistical significance （P〈0.05）. CONCLUSIONS： Rapid reporting system of ADR in the hospital is beneficial to improve the efficiency and guarantee the quality of the reports. It also can expand the coverage of the monitoring network, and can lay the foundation for drug safety scientific evaluation and monitoring.