精神病患者梅毒感染的检测结果分析

Analysis of the detecting results of syphilis infection among psychiatric patients

目的了解精神病患者梅毒的感染情况,为精神病患者梅毒的预防、治疗及控制提供参考。方法以雅安市第四人民医院2015年6月-2016年6月收治的756例符合《国际疾病分类(第10版)》(ICD-10)诊断标准的精神病患者为研究对象,对其分别采用梅毒甲苯胺红不加热血清试验(TRUST)和梅毒螺旋体明胶颗粒凝集试验(TPPA)进行抗梅毒螺旋体抗体检测。结果本次共检测出梅毒抗体阳性51例,男性和女性分别为28例、23例,其中TRUST阳性/TPPA阴性男性1例,女性3例,TPPA阳性/TRUST阴性男性17例,女性9例,TRUST/TPPA双阳性男性10例,女性11例;女性感染率高于男性,但差异无统计学意义(7.67%vs.6.14%,χ~2=0.670,P=0.413)。结论精神病患者中存在一定比例的梅毒感染者,且感染情况在性别上无统计学差异。

Objective To investigate the incidence of syphilis infection on psychiatric patients and to provide references for the prevention, treatment and control of syphilis in psychiatric patients. Methods A total of 756 psychiatric patients who met the diagnostic criteria of International Classification of Diseases, tenth edition （ICD - 10） from June 2015 to June 2016 in the Fourth People s Hospital of Yaan were recruited. The toluidine red unheated - serum test （TRUST） and treponema pallidum particle agglutination test （TPPA） were used to detect the treponema pallidum antibody （anti - TP）. Results A total of 51 people who having anti - TPs were detected, in which including 28 males and 23 females 4 cases of TRUST positive/TPPA negative （ male 1 case, female 3 cases） , 26 cases of TPPA positive/TRUST negative （male 17 cases, female 9 cases） , and 21 cases of TRUST positive/TPPA positive （male 10 cases, female 11 cases）. The positive rate of women was higher than that of men, but the difference was not statistically significant （7.67% vs. 6.14% , =0.670, P =0.413）. Conclusion There is a certain percentage of syphilis infection in psychiatricpatients, and there is no statistically significant difference in gender.