二甲双胍联合阿卡波糖治疗2型糖尿病并高血脂症的临床疗效分析

Analysis of Clinical Curative Effect of Metformin and Acarbose in Treatment of Type 2 Diabetes and Hyperlipidemia

目的分析二甲双胍联合阿卡波糖治疗2型糖尿病(T2DM)并高血脂症的疗效。方法收集该院内分泌科住院的T2DM伴高血脂症患者364例,其中采用二甲双胍单药治疗182例为对照组,采用二甲双胍联合阿卡波糖治疗的182例为联合组。比较治疗前后两组血糖、血脂指标变化及治疗3个月后两组疗效。结果治疗后,两组患者各项血糖及血脂指标均有明显下降(P<0.05),且联合组均优于对照组(P<0.05)。联合组总有效率为94.51%,显著高于对照组的73.63%(P<0.05)。结论二甲双胍联合阿卡波糖治疗2型糖尿病伴高脂血症可显著改善患者血糖水平和血脂水平,临床疗效值得肯定。

Objective To analyze the curative effect of metformin and acarbose in treatment of type 2 diabetes and hyperlipidemia. Methods 364 cases of patients with type 2 diabetes and hyperlipidemia in our hospital were collected and divided into two groups with 182 cases in each, the control group were treated with single mefformin, while the combined group were treated with type 2 diabetes and hypedipidemia, and the blood glucose, blood liquid, and curative effect after 3-month treatment were compared before and after treatment. Results After treatment, various blood glucose and blood liquid indexes of the two groups obviously decreased（P〈0.05）, and the indexes in the combined group were better than those in the control group（P〈0.05）, and the total effective rate was obviously higher than that in the control group（94.51% vs 73.63%）（P〈0.05）. Conclusion The metformin and acarbose in treatment of type 2 diabetes and hyperlipidemia can obviously improve the blood glucose and blood liquid levels of patients and the clinical curative effect is worth recognition.