导管接触溶栓与机械辅助吸栓治疗急性髂股静脉血栓的对比研究

Comparative Study of Early Therapeutic Effects of Catheter-directed Thrombolysis and Pharmaco Mechanical Thrombolysis for Lower Extremity Deep Vein Thrombosis

目的:评价导管接触溶栓与机械辅助吸栓治疗急性髂股静脉血栓的临床效果。方法:回顾性分析162例急性下肢深静脉血栓(髂股静脉血栓)形成患者临床资料,其中导管溶栓治疗组(A组)80例、机械辅助吸栓组(B组)82例,比较两组患者治疗后患肢深静脉溶栓率、消肿率、并发症发生率、治疗时间的差异。结果:急性下肢髂股静脉血栓溶栓率B组(46.45±11.56)%显著高于A组(32.05±10.7)%(P<0.05)。患肢消肿率B组(68.68±10.75)%和A组(41.34±11.26)%有明显统计学差异(P<0.05)。两组并发症发生率无明显统计学意义。两组溶栓时间A组明显长于B组,两组间比较有明显统计学差异。结论:机械辅助吸栓治疗急性髂股静脉血栓早期疗效好于导管接触溶栓。

Objective：To evaluate the early clinical effect of catheter-directed thrombolysis （CDT） and Pharmaco Mechanicall thrombolysis （PMT） treatment in acute deep venous thrombosis （DVT）.Methods：Retrospective analysis 162 cases of acute lower extremity deep venous thrombosis inpatients with clinical data,including catheter-directed thrombolysis group include 80 cases （group A）,Pharmaco Mechanical thrombolysis treatment group include 82 cases （group B）.The deep vein thrombolysis rate,treatment time,and limb swelling remission rate of the two groups were evaluated.Results：For the central type DVT,group B highest thrombolysis rate of deep vein （46.45± 11.56）%,which was significantly higher than that of group A （32.05± 10.7） % （P 〈 0.05）.For the central type DVT,group B had limb swelling remission rate （68.68± 10.75） %,there was significant statistical difference with group A （41.34± 11.26） % （P 〈 0.05）.The complications rate of the two groups was no obvious statistical significance.For The thrombolysis time,group A was longer than group B,there was significant statistical difference （P 〈 0.05）.Conclusion：The early clinical effect of Pharmaco Mechanical thrombolysis treatment for lower extremity DVT is better than that of catheter-directed thrombolysis.