摘要
目的:探讨肿瘤异常糖链糖蛋白(tumor abnormal protein,TAP)、癌胚抗原(carcinoembryonic antigen,CEA)与糖链抗原153(carbohydrate antigen 153,CA153)在乳腺癌早期诊断中的临床价值。方法:收集45例乳腺癌患者为研究组,49例正常体检人群为对照组,比较各肿瘤志记物的敏感度、特异度、准确度等指标。结果:在乳腺癌组患者中,TAP,CEA,CA153检测敏感度分别为80.00%,8.89%,6.67%;特异度分别为100.00%,97.96%,100.00%,准确度分别为90.42%,55.32%,55.32%。结论:肿瘤TAP检测优于肿瘤标志物CEA和CA153检测,可作为乳腺癌的早期筛查指标。
Objective: Our objective is to explore the clinical application value of serum tumor abnormal protein(TAP), carcinoembryonic antigen(CEA) and carbohydrate antigen 153(CA153) in the early diagnosis of breast cancer. Methods: Forty-five patients with breast cancer were collected as experimental group and 49 normal population as control group. The sensitivity, specificity, accuracy rate and other indicators were compared. Results: In experimental group, the sensitivity of TAP, CEA and CA153 were 80.00%, 8.89% and 6.67% respectively. The specificity of those indicators were 100.00%, 97.96% and 100.00% respectively. The accuracy those indicators were 90.42%, 55.32% and 55.32% respectively. Conclusion: The TAP had more clinical value than CEA and CA153 as an indicator and could be considered as a better screening index in the early diagnosis of breast cancer.
出处
《临床与病理杂志》
2017年第6期1211-1215,共5页
Journal of Clinical and Pathological Research
基金
苏州市科技局应用基础研究计划(SYS201571)~~
关键词
异常糖链糖蛋白
癌胚抗原
糖链抗原153
早期诊断
乳腺癌
tumor abnormal protein
carcinoembryonic antigen
carbohydrate antigen 153
early diagnosis
breast cancer