应用改良快速顺序诱导快速康复外科全麻效果观察

Clinical Effect of the Modified Rapid Sequence Induction on Fast-track Surgery by General Anesthesia

目的:探讨改良快速顺序诱导用于快速康复外科全麻患者的临床效果。方法:随机选择我院2015年1月1日至2015年12月31日胃肠外科行腹腔镜下胃癌根治手术患者共计100例,随机分为观察组和对照组各50例,分别行改良快速顺序诱导和经典快速顺序诱导。并比较术前基本情况、术中情况、术后情况及免疫相关指标。结果:两组患者手术时间、手术方式、肿瘤分期方面分析比较,差异无统计学意义(P>0.05);观察组术中出血量及补液量均少于对照组,差异具有统计学意义(P<0.05)。观察组术后排气时间、排便时间、住院时间、进食时间均明显早于对照组,差异具有统计学意义(P<0.05)。术前、术后1日、术后3日、出院前,Ig G差异均具有统计学意义(P<0.05)。结论:改良快速顺序诱导用于快速康复外科全麻患者可加速患者术后的恢复,提升术后免疫力。

Objective：To investigate the clinical effect of modified rapid sequence induction on fast-track surgery by general anesthesia.Methods：A controlled randomized clinical trial was conducted from Jan 1,2015 to Dec 31,2015.A total of 100 patients with gastric cancer were randomized into two groups：the observation group undergoing modified rapid sequence induction and the control group undergoing conventional rapid induction.The preoperative fundamental condition,intraoperative condition,postoperative condition and markers of immune function.Were compared between two groups.Results：The bleeding,intraoperative transfusion of observation group were less than the control group.In intraoperative condition,compared with the control group,the operating time,modus operandi,tumor stage were not significantly different （all P〉0.05）;while that in bleeding,intraoperative transfusion were significantly different （all P〈 0.05）.The clinical recovery of the observation group was earlier than the control group.After operation,statistically significant differences were found for first bowel sounds,defecation,hospital stay,initiation of soft diet （all P〈0.05）.Before operation,postoperative day 1,postoperative day 3,prior to discharge,the IgG was significantly different（P〈0.05）.Conclusions：The modified rapid sequence induction could be effectively used in general anesthesia patients,which could accelerate the clinical recovery and improve the immunity after elective open surgery of gastric carcinoma patients.