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冠状动脉介入治疗术联合替罗非班治疗急性心肌梗死的临床疗效及其安全性

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摘要 目的探讨冠状动脉介入治疗术联合替罗非班治疗急性心肌梗死(AMI)的临床疗效及其安全性。方法选取如皋市人民医院2015年2月—2016年5月收治的老年AMI患者81例,根据治疗方式的不同分为对照组(n=40)和观察组(n=41)。对照组患者入院后给予冠状动脉介入术治疗,观察组患者在对照组基础上给予替罗非班治疗。比较两组患者术后血管再通率、病死率及住院时间;术后出血、心脏不良事件发生情况及治疗前后心肌梗死溶栓疗法危险评分系统(TIMI)评分。结果观察组患者血管再通率、病死率低于对照组,住院时间短于对照组(P<0.05)。两组患者术后出血率比较,差异无统计学意义(P>0.05);观察组患者心脏不良事件发生率低于对照组(P<0.05)。治疗前,两组患者TIMI评分比较,差异无统计学意义(P>0.05);治疗后,观察组患者TIMI评分低于对照组(P<0.05)。结论采用冠状动脉介入治疗术联合替罗非班治疗AMI的临床疗效确切,可有效降低患者病死率,缩短住院时间,改善病情,促进疾病康复,且安全性高。
作者 周明龙
出处 《临床合理用药杂志》 2017年第18期50-51,共2页 Chinese Journal of Clinical Rational Drug Use
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