中医整体疗法联合甲状旁腺全切加自体移植术治疗继发性甲状旁腺功能亢进症研究

Study of Chinese Medicine Holistic Therapy Combined with Total Parathyroidectomy and Autografting for Secondary Hyperparathyroidism

目的:观察中医整体疗法联合甲状旁腺全切加自体移植术的中西医结合疗法治疗继发性甲状旁腺功能亢进症的临床疗效。方法:在甲状旁腺全切加自体甲状旁腺移植术的基础上采用中医综合疗法,包括口服中药汤剂和中药制剂,中药结肠透析(保留灌肠)等对症处理治疗继发性甲状旁腺功能亢进症。结果:治疗前后比较,皮肤瘙痒线性评分、骨痛分级情况,差异均有统计学意义(P<0.01);肌无力评分,差异无统计学意义(P>0.05);血红蛋白于术后第2天之后呈逐渐下降,至术后3月后有升高趋势。结论:采用中医整体疗法联合甲状旁腺全切加自体甲状旁腺移植术能有效降低严重的并发症,减少手术风险,提高中西医药治疗慢性肾功能衰竭继发性甲状旁腺功能亢进症的临床疗效。

Objective：To observe the clinical effect of the integrated Chinese and western medicine therapy--Chinese medicine（CM） holistic therapy combined with total parathyroidectomy and autografting for secondary hyperparathyroidism.Methods：Based on total parathyroidectomy and autografting,CM holistic therapy including decoction,preparation and colon dialysis（retention enema） and other expectant treatment was applied for secondary hyperparathyroidism. Results：Compared the linear evaluation of pruritus and pain assessment in the two groups before and after treatment,differences were both significant（P〈0.01）. There was no significance being found in the comparison of myasthenia score in both groups（P〉0.05）. On the second day after operation, hemoglobin was gradually reduced, but it tended to increase three months after the operation. Conclusion： CM holistic therapy combined with total parathyroidectomy and autografting for secondary hyperparathyroidism can reduce serious complication, decrease operative risk and enhance the clinical effect of treating chronic renal failure and secondary hyperparathyroidism.