保妇康栓和朗依治疗妊娠合并外阴阴道假丝酵母菌病的最小成本分析

Cost-Minimization Analysis of Baofukang Compared with Langyi in the Treatment of Pregnancy with Vulvovaginal Candidiasis

目的评价保妇康栓和朗依(硝呋太尔制霉素阴道软胶囊)治疗妊娠合并外阴阴道假丝酵母菌病的经济性,为合理用药及相关决策提供参考。方法本研究基于二次文献进行Meta分析,以获取药物经济学评价中的有效性、安全性数据;结合相应治疗规范与临床专家建议,确定治疗路径并据此计算总的直接医疗成本。基于全社会角度,运用最小成本分析法,进行药物经济学评价。结果保妇康栓组的总直接医疗成本低于朗依组。敏感性分析证明确定性分析结果稳定。结论与朗依相比,保妇康栓治疗妊娠合并外阴阴道假丝酵母菌病的经济性更好。

OBJECTIVE To conduct an economic evaluation of Baofukang versus Langyi in the treatment of pregnancy with vulvovaginal candidiasis by means of cost-minimization analysis. Furthermore, provide reference for reasonable clinical prescription and decision-making. METHODS Meta-analysis was conducted to support the safety data and effectiveness data of pharmacoeconomic e- valuation based on literature review; guidelines and clinical experts＇ suggestion were used to find out treatment routes to calculate total direct medical costs. Cost-minimization analysis was conducted from the societal perspective. RESULTS The total direct medical costs of group Baofukang was lower than group Langyi＇s. Sensitivity analysis indicated the results were robust. CONCLUSION In contrast with Langyi, Baofukang is a more economic therapy in the treatment of pregnancy with vulvovaginal candidiasis.