期刊文献+

阿托伐他汀与辛伐他汀治疗冠心病心绞痛效果观察 被引量:2

下载PDF
导出
摘要 目的:探讨阿托伐他汀与辛伐他汀治疗冠心病心绞痛的临床效果以及安全性。方法:根据不同的治疗药物,将2014年5月至2016年5月惠州市惠城区小金口人民医院收治的107例冠心病心绞痛患者分为阿托伐他汀组(n=54)与辛伐他汀组(n=53),比较治疗前、后两组患者心绞痛的疼痛程度、持续时间、发作次数以及硝酸甘油用量、血清血脂变化情况。随访半年,比较两组患者的心血管事件发生率。结果:与本组治疗前比较,治疗后两组患者心绞痛发作时的疼痛程度明显减轻、持续时间明显缩短、硝酸甘油用量及发作次数明显减少,差异具有统计学意义(P<0.05),但上述指标组间比较,差异无统计学意义(P>0.05);治疗3个月后组内比较低密度脂蛋白-胆固醇(LDL-C)、三酰甘油(TG)、总胆固醇(TC)比治疗前下降明显、高密度脂蛋白-胆固醇(HDL-C)比治疗前明显上升,上述血清血脂水平组间比较,差异无统计学意义(P>0.05);两组患者心血管事件发生率比较,差异无统计学意义(P>0.05)。结论:阿托伐他汀与辛伐他汀两种药物在冠心病心绞痛的临床治疗中均有明显效果,能够有效调节患者血脂水平。
出处 《深圳中西医结合杂志》 2017年第8期78-80,共3页 Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
  • 相关文献

二级参考文献82

  • 1陆再英,钟南山.内科学[M].7版北京:人民卫生出版社.2008:394.
  • 2Lawson WE, Hui JC, Lang G. Treatment benefit in the enhanced external counterpulsation consortium. Cardiology, 2000,94 ( 1 ) :31-35.
  • 3Ryden L, Standl E, Bartnic M, et al. Guideline on diabetes, prediabetes and cardiovascular disease:executive summary. The Task Force on Diabetes and Cardiovascular Disease of European Society of Cardiology (ESC) and of the Euopean Association for the Study of Diabetes(EASD). Eur Heart J,2007,28( 1 ) :88-136.
  • 4Crawford MH, Bernstein SJ, Deedwania PC, et al. ACC/AHA Guidelines for Ambulatory Electrocardiography. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines ( Committee to Revise the Guidelines for Ambulatory Electrocardiography). Developed in collaboration with the North American Society for Pacing and Electrophysiology.J Am Coll Cardiol,1999,34(3) :912-948.
  • 5Campeau L. Letter: Grading of angina pectoris. Circulation 1976 :54(3) :522-523.
  • 6O'Rourke RA, Brundage BH, Froelicher VF, et al. American College of Cardiology/American Heart Association Expert Consensus Document on electron-beam computed tomography for the diagnosis and prognosis of coronary artery disease. J Am Coll Cardiol, 2000,36(1) :326-340.
  • 7Gibbons Pal, Abrams J, Chatterjee K, et al. ACC/AHA 2002 guideline update for the management of patients with chronic stable angina-sunanary article: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines (Committee on the Management of Patients With Chronic Stable Angina). J Am Coll Cardiol, 2003,41 ( 1 ) : 159-168.
  • 8Malik S, Wong ND, Franklin SS, et al. Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults. Circulation, 2004,110(10) :1245-1250.
  • 9Girman CJ, Rhodes T, Mercuri M,et al. The metabolic syndrome and risk of major coronary events in the Scandinavian Simvastatin Survival Study (4S) and the Air Force/Texas Coronary Atherescleresis Prevention Study (AFCAPS/TexCAPS). Am J Cardiol,2004,93 ( 2 ) : 136-141.
  • 10Kjekshus JK, Maroko PB, Sobel BE. Distribution of myocardial injury and its relation to epicardial ST-segment changes after coronary artery occlusion in the dog. Cardiovasc Res,1972,6(5) :490-499.

共引文献2137

引证文献2

二级引证文献10

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部