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放射治疗前列腺癌原发灶对远隔骨转移性疼痛缓解的临床观察 被引量:10

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摘要 目的探讨放射治疗前列腺癌原发灶对远隔骨转移性疼痛缓解的临床效果。方法选择2010-2013年该院确诊为前列腺癌骨转移伴有疼痛的患者79例分为两组。联合治疗组40例采用前列腺局部放射治疗联合内分泌治疗,对照组39例单用内分泌治疗。按照实体瘤疗效评价标准和疼痛数字评分法评估治疗后两组的疗效,观察不良反应和疼痛生化指标变化。结果联合治疗组治疗后骨转移疼痛症状明显改善,疼痛缓解率优于对照组(P<0.05)。血清前列腺特异性抗原、Ⅰ型胶原吡啶交联终肽较对照组明显下降(P<0.01)。结论前列腺癌原发灶放射治疗联合内分泌治疗能有效地缓解前列腺癌骨转移疼痛,改善生活质量。
出处 《重庆医学》 CAS 北大核心 2017年第20期2826-2829,共4页 Chongqing medicine
基金 重庆市医学重点研究室建设基金资助项目(2007-14) 重庆市万州区科委基金项目(2013-45)
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