HIV合并TP/HCV/HBV感染者结果分析

HIV merger TP/HCV/HBV infection results analysis

目的分析人类免疫缺陷病毒(HIV)合并梅毒螺旋体(TP)、丙型肝炎病毒(HCV)、乙型肝炎病毒(HBV)感染的情况。方法选择2012年6月1日至2016年12月31日到曲靖市第二人民医院就诊的364例HIV感染者,全部患者经酶联免疫吸附试验(ELISA)进行初筛,HIV抗体初筛检测阳性者抽取血样后送往曲靖市疾病预防控制中心(CDC)确证实验室进行确证检测;同时检进行梅毒螺旋体凝集试验(TPPA)、HCV抗体(ELISA检测)、HBV血清抗原抗体标志物(HBs Ag,HBs Ab,HBeAg,HBe Ab,HBcAb)检测,并对检测结果进行统计分析。结果 364例HIV感染者中混合感染共93例,男性71例,女性22例;感染TP、HCV、HBV者分别为43例(11.8%)、32例(8.8%)、7例(1.9%);HIV与TP和HCV共同感染者7例(1.9%);HIV与TP和HBV共同感染者2例(0.5%)。结论 HIV感染者存在一定比例合并TP、HCV、HBV的混合感染情况,且HIV单纯合并TP或HCV的混合感染者感染率高,同时也存在HIV与TP和HCV、HIV与TP和HBV共同感染者。建议对HIV感染者同时进行TP、HCV、HBV检测。

Objective Analysis of the infection of the human immunodeficieney virus （HIV） with syphilis spirals （TP）, hepatitis C virus （HCV）, hepatitis B virus （HBV） infection. Methods Choice on June 1, 2012 to December 31, 2016 in Qujing City Second People＇s Hospital, 364 cases of HIV infection, all patients by enzyme- linked immunosorbent assay （ELISA） for early screening, early HIV antibody screening test positive for after blood samples taken to Qujing City Center for Disease Control and Prevention （CDC） confirmed were identified by laboratory testing; At the same time detection for treponema pallidum agglutination test （TPPA）, HCV antibody （ELISA） and serum HBV antigen antibody markers （HBsAg, HBsAb, HBeAg, HBeAb and HBcAb） detection, and the testing results were analyzed. Results Of the 364 eases of HIV infection, 93 cases, 71 men and 22 women; Infection of TP, HCV, and HBV were 43 cases （11.8%）, 32 cases （8.8%）, and 7 cases （1.9%）; 7 cases of HIV/TP and HCV co-infection （1.9%）; HIV/TP and HBV were co-infected 2 （0.5%）. Conclusions People living with HIV has certain proportion with TP, a mixture of HCV, HBV infection status, a mixture of simple combination of TP and HIV or HCV infection rate is high, at the same time there are HIV and HCV, HIV and TP and TP and HBV infcetion. It is recommended that HIV patients should be tested for TP, HCV, and HBV.