职业性铅接触对男性精液质量的影响分析

Effect of occupational lead exposure on male semen quality

目的探讨职业性铅接触对男性精液质量的影响。方法选择163例职业性铅接触的男性为接触组,根据工作年限将其分为A组(工龄≤10年)和B组(工龄>10年),对照组为150例非职业性铅接触的健康正常男性。采用SQA-V型精子质量分析系统对以上受试者精液标本的各项主要参数进行对比分析,同时采用改良巴氏染色法进行精子形态评价。结果与对照组男性的精子密度、活率、前向运动率及正常精子形态率相比较,接触组中A组患者与对照组差异有统计学意义(P<0.05),而接触组中B组患者与对照组比较差异有非常显著性(P<0.01)。结论职业性铅接触对男性精液质量有一定的影响,长期接触可能会引起男性生殖系统毒性效应,导致男性不育。

Objective： To investigate the effect of occupational exposure to lead on semen quality in male. Methods： A total of 163 patients with occupational exposure to lead were selected as exposure group. According to their working years, they were divided into group A （seniority≤10 years） and group B （seniority：〉10 years） . The control group was 150 healthy non-Normal male. The main parameters of semen samples were analyzed by SQA-V sperm quality analysis system, and the sperm morphology was evaluated by modified Papanicolaou staining. Results： Compared with the control group, the differences of sperm density, viability, forward movement rate and normal sperm morphology between the group A and the control group were statistically significant （P〈0.05） , while exposure patients in group B group had significant differences compared with the control group （P 〈0.01 ） . Conclusion： Occupational exposure to lead on the quality of male semen have a certain impact, long-term exposure may cause male reproductive system toxic effects thus leading to male infertility.