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间充质干细胞治疗缺血性脑卒中的研究进展 被引量:1

Recent advance in mesenchymal stem cells in treatment of ischemic stroke
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摘要 大量的动物实验和临床试验证实了间充质干细胞独特的生物学特性以及对脑缺血的治疗效果,间充质干细胞移植治疗为缺血性脑卒中的治疗带来了希望。本文围绕间充质干细胞治疗缺血性脑卒中的作用机制、移植途径、时间窗和示踪方法综述如下。 The treatment ofischemic stroke remains clinically a daunting task as few therapeutic strategies have proven to be effective. So far, a large number of animal experiments and clinical trials have confirmed the unique biological characteristics and therapeutic effect of mesenchymal stem cells on cerebral ischemia. Therapeutic strategies based on transplantation of mesenchymal stem cells hold great promise for treatment of ischemic stroke. Here, we review mechanisms of mesenchymal stem cells in the treatment ofischemic stroke, transplantation pathways, time windows and tracer methods, providing a good reference to research and apply mesenchymal stem cells in the treatment of stroke.
出处 《中华神经医学杂志》 CSCD 北大核心 2017年第7期747-751,共5页 Chinese Journal of Neuromedicine
关键词 缺血性脑卒中 间充质干细胞 干细胞移植 时间窗 Ischemic stroke Mesenchymal stem cell Transplantation Time window
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