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血肌酐正常冠心病患者危险因素分析及血清胱抑素C检测意义 被引量:6

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摘要 目的分析冠心病血肌酐(SCr)正常患者病情进展危险因素,探讨血清胱抑素C(Cys C)指标变化的提示意义。方法选取温州医科大学附属第三医院2014年10月—2015年10月80例SCr正常冠心病患者(观察组)及80例健康体检者(对照组)为研究对象,对2组性别、年龄、冠心病家族史、吸烟史、糖尿病史、Cys C、血尿素氮(BUN)进行比较,采用Logistic多因素分析筛选SCr正常冠心病患者危险因素。结果 2组性别、年龄、吸烟史、糖尿病史、Cys C差异有统计学意义(P<0.01),即男性、年龄≥60岁、有吸烟史、有糖尿病史、Cys C>1.31 mg/L这5项因素与冠心病发病有关;而冠心病家族史、BUN差异无统计学意义(P>0.05)。Logistic多因素分析提示年龄、性别、Cys C是SCr正常冠心病患者的独立危险因素。结论 Cys C为SCr正常冠心病患者的危险因素,对SCr正常的冠心病患者进行Cys C检测有利于掌握病情进展。当患者Cys C水平>1.09 mg/L时,要密切关注患者病情变化,及时采取临床治疗措施;当患者Cys C水平>1.31 mg/L时,应采取临床治疗措施控制冠心病进展,并结合其他检查项目实施治疗。
出处 《中华全科医学》 2017年第9期1626-1628,共3页 Chinese Journal of General Practice
基金 瑞安市科技局(YY2014043) 上海市卫计委重点项目(20134009)
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