星状玻璃体变性的临床研究进展

Progress in clinical research of asteroid hyalosis

星状玻璃体变性(asteroid hyalosis,AH)是一种常见的临床疾病,由于极少影响视力,一直被认为是一种良性疾病,患者多因其他眼疾就诊时发现本病,具体机制不清楚。B超的特征性表现有助于本病的诊断,对于合并其他眼底疾病的患者,OCT和FFA可以降低星状小体的干扰,提高眼底的可视性。临床上一般很少对单纯AH进行临床干预,最近有研究表明,本病可合并其他多种眼科疾病,合并白内障时,AH的存在可使植入的硅胶人工晶状体发生钙化,而钙化的IOL大多需要进行置换,关于AH合并白内障是否应Ⅰ期联合玻璃体切割手术仍存在争议。本文对有关AH的发病影响因素、相关辅助检查以及治疗做一综述,以期提高对本病的认识水平。

Asteroid Hyalosis （AH） is a common clinical disease,which has been considered a benign disorder as it rarely impairs visual acuity.It was often discovered when the patient was treated for other eye diseases.The mechanism was unclear.Its characteristic B-ultrasound property makes the B-ultrasound a very helpful diagnostic technique.In the case of the patients with other fundus diseases associated with AH,optical coherence tomography （OCT） and fluorescein angiography （FA） may be used to reduce the interference from asteroid bodies,therefore improve the fundus visibility.Recent studies have shown that AH can incorporate with many other eye diseases.For example,in patients with cataracts,asteroid hyalosis can cause surface calcification of silicone plate intraocular lenses,which in most cases may lead to the need for explantation of the calcified intraocular lenses.The efficacy of pars plana vitrectomy （PPV）,the removal of some,or all,of the eye＇s vitreous humor for AH remains controversial.In this paper,we provide a review of the recent literature on AH disease： the etiology,diagnosis and treatment.We hope to thus improve the awareness and outcomes of AH disease.