摘要
实验动物的检疫验收是一项控制动物在流通环节免受污染、防止疫病发生和传播的重要工作,是实现实验动物质量标准化的关键。Beagle犬因其遗传稳定,对环境的适应能力和抗病力较强,在试验中反应一致性好,是被国际所公认的专用实验犬,在药物安全性评价实验中应用广泛。建立药物GLP机构试验用Beagle犬检疫验收的标准操作规程,细化检疫验收的技术要点,加强检疫人员的技术培训,努力提高检疫水平,最终确保实验动物质量。
The quarantine inspection and acceptance of laboratory animals is an important work,which can protect animals from pollution,occurrence and spread of diseases in the surounding area,and it is the key point to realize the quality standardization of laboratory animals. Beagle dogs are acknowledged widely as specialized laboratory dogs which is widely employed in experiments of drug safety evaluation because of the good genetic stability,environmental adaptability,disease resistance and consistency testing in the experiments. Establishment of standard operating procedures of beagle dog quarantine acceptance check for drug GLP organization tests,refining technical points,strengthen the technical training of quarantine officers,and efforts to improve the level of quarantine are needed to finally ensure the quality of laboratory animals.
出处
《中国比较医学杂志》
北大核心
2017年第6期63-67,共5页
Chinese Journal of Comparative Medicine
关键词
GLP
BEAGLE犬
检疫
Good laboratory practice
Beagle dog
Quarantine
Drug safety evaluation
Laboratory animals