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IMC在肿瘤免疫逃逸中作用机制的研究进展

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摘要 未成熟骨髓细胞(immature myeloid cell,IMC)是一个异质造血细胞群体,它主要存在于骨髓,并少量存在于外周血中。在健康个体中,IMC在骨髓内产生并分化为成熟的粒细胞、巨噬细胞或DC。然而,在病理条件下,例如癌症,IMC的分化途径受到部分阻滞而导致其大量增殖,IMC的大量增殖大大促进了肿瘤的生长和转移,引发了肿瘤的免疫逃逸。本文就IMC在肿瘤免疫逃逸中作用机制的研究进展进行综述。
出处 《现代免疫学》 CSCD 北大核心 2017年第4期346-349,共4页 Current Immunology
基金 河南省基础与前沿技术研究计划项目(132300410448)
关键词 IMC 肿瘤 免疫逃逸
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