导致消化性溃疡合并出血相关因素的Logistic回归分析

The Related Factors of Result from Peptic Ulcer Combined Bleeding by Logistic Regression Analysis

目的探讨消化性溃疡合并出血患者的危险因素。方法将2016年3月-2017年3月在我院治疗的消化性溃疡患者288例纳入本研究,发生消化性溃疡并出血者为观察组,121例;未出血患者纳入对照组,167例。采集两组患者临床资料,采用χ~2检验筛选出导致消化性溃疡合并出血的可能相关因素,再进行多因素非条件Logistic回归分析。结果经多因素分析发现,年龄≥75岁、Hp感染、口服非甾体药物是导致消化性溃疡合并出血的独立危险因素,而口服PPI是保护因素(P<0.05)。结论年龄≥75岁、Hp感染、口服非甾体药物是导致消化性溃疡合并出血的独立危险因素,而口服PPI是保护因素。

Objective To explore the risk factors for patients with peptic ulcer. Methods 288 patients with peptic ulcer treated in our hospital from March 2016 to March 2017 were included in this study. 121 cases of peptic ulcer and bleeding in the observation group; No bleeding patients were included in the control group, 167 cases. The clinical data of two groups of patients were collected, and χ2 test was used to select the possible related factors that resulted in the combined bleeding of peptic ulcer, and then multifactor non-conditional Logistic regression analysis was performed. Results Multi-factor analysis showed that, age 75 or higher, Hp infection, oral non-steroidal drugs were the independent risk factors of peptic ulcer with bleeding, and oral PPI was the protective factor（P〈 0.05）. ConclusionThe risk factors of peptic ulcer combined with haemorrhage are independent risk factors, and oral PPI is the protective factor.