缬沙坦联合氨氯地平治疗社区老年原发高血压合并糖尿病疗效观察

Curative Effect Observation on Valsartan With Amlodipine Therapy Community Senile Primary Hypertension Diabetes Mellitus

目的观察缬沙坦联合氨氯地平治疗社区老年原发高血压合并糖尿病疗效。方法选择2016年4月—2017年1月期间在我院接受治疗的社区老年原发高血压合并糖尿病患者56例作为研究对象,随机划入观察组和对照组,其中观察组28例,对照组28例,分别接受缬沙坦联合氨氯地平治疗和氨氯地平单用治疗,比较两组患者的血糖和血压水平。结果观察组患者空腹血糖(5.2±0.6)mmol/L,餐后2 h血糖水平(8.2±0.9)mmol/L,收缩压(117.3±5.2)mm Hg,舒张压(86.5±5.9)mm Hg;对照组患者空腹血糖(7.3±0.8)mmol/L,餐后2 h血糖水平(10.8±0.7)mmol/L,收缩压(138.4±5.6)mm Hg,舒张压(97.3±6.3)mm Hg;组间差异有统计学意义(P<0.05)。结论缬沙坦联合氨氯地平治疗社区老年原发高血压合并糖尿病疗效优于氨氯地平单用,值得临床应用与推广。

Objective To observe the curative effect of the combined diabetes mellitus in the treatment community of valsartan in the treatment community. Methods 56 cases senile primary hypertension diabetes mellitus patients in community were selected from April 2016 to January 2017 treated in our hospital and considered as the research objects, they were randomly grouped into observation group and control group, the observation group of 28 cases, 28 cases in the control group, respectively treated with valsartan combined amlodipine and amlodipine therapy alone, two groups of patients with blood sugar and blood pressure levels were compared. Results In the observation group, the fasting glucosewas（5.2±0.6）mmol/L, and 2 h blood sugar level was（8.2±0.9）mmol/L, and the systolic blood pressure was（117.3±5.2） mmHg, and the diastolic blood pressure was（86.5±5.9）mmHg. In the control group, the fasting glucose was（7.3±0.8）mmol/L, and 2 h blood sugar level was（10.8±0.7） mmol/L, systolic blood pressure was（138.4±5.6）mmHg,and diastolic blood pressure was（97.3±6.3）mmHg. The difference in the group was statistically significant（P 〈 0.05）. Conclusion The combination of valsartan combined with ammonia chloride in the treatment of elderly primary hypertension in the community is better than that of ammonia chloride, which is worth clinical application and promotion.