脂肪移植改善肉芽肿性乳腺炎术后局部缺损的应用体会

The application of fat transplantation to repair local defect of granulomatous mastitis after operation

目的探讨脂肪移植法修复肉芽肿性乳腺炎术后乳房局部缺损畸形的可行性和安全性。方法回顾性分析85例脂肪移植填充肉芽肿性乳腺炎术后乳房局部缺损的病例临床资料。结果 85例患者乳房局部缺损外形明显改善,缺损范围小于1/4象限的患者,术后改善优良率为82.5%。缺损在1/4象限到1/2象限的患者术后优良率为36.1%,2组优良率比较的差异有统计学意义(P<0.05)。2组均无手术相关并发症,随访期间未见肉芽肿性乳腺炎局部复发,受移植乳腺未见乳腺良恶性肿瘤发生。结论针对肉芽肿性乳腺炎术后乳房缺损,采用脂肪移植的方法纠正安全有效,且缺损范围小于1/4象限的患者更为有效。

Objective To explore the feasibility and safety of fat grafting repairing local defect of granulomatous mastitis after operation. Methods A retrospective analysis was performed with 85 cases of fat grafting repair local defects with granulomatous mastitis after operation. Results 85 cases of breast local defect shape improved significantly. In patients with defect less than 1/4 quadrant,the excellent rate of postoperative improvement was 82.5%. The excellent rate of patients with defect in 1/4 quadrant to 1/2 quadrant was 36.1%. The excellent rate of two groups was statistically significant（ P〈0.05）. No surgery related complications. During the follow-up,there were no local recurrence of granulomatous mastitis and breast benign and malignant tumors occurred in transplanted breast. Conclusion According to the postoperative breast defect of granulomatous mastitis,using fat transplantation to correct is safe and effective,which is more effective in patients with defect less than 1/4 quadrant.