脑胶质瘤生物学标记物和分子病理分型的研究进展

Research advances on the biological markers and classification of molecular pathology of glioma

脑胶质瘤作为最常见的颅内原发肿瘤,由于其诊断方式的局限性,造成患者预后较差.如何尽早精确诊断脑胶质瘤并制定相应的针对性治疗计划成为治疗胶质瘤的难题之一.随着临床研究的不断扩大和深入,生物学标记物及分子病理分型能够为多种疾病的诊断及治疗提供帮助.本文重点阐述脑胶质瘤生物学标记物及分子病理分型的研究进展,旨在为今后的胶质瘤临床诊断及治疗提供科学指导,改善患者预后,提高其生存质量.

Brain glioma is the most common intracranial primary tumor, due to the limitations of its diagnostic methods, resulting in poor prognosis of patients. How to diagnose brain gliomas as soon as possible and develop appropriate targeted treatment plans become one of the problems in the treatment of gliomas. With development of clinical research and scientific advances, biology markers and molecular pathology have been found to be helpful in the diagnosis and treatment of various diseases. Therefore, this paper focuses on research progress of biomechanical markers and molecular pathology of glioma, which are aimed at providing sci- entific guidance for the future of glioma clinical diagnosis and treatment, and improve the prognosis and life quality of patients.