高脂血症性与胆源性急性胰腺炎患者血脂、血淀粉酶、尿淀粉酶水平的比较

Comparison of glycolipid,amylase and urine amylase levels in patients with hyperlipidemia and biliary acute pancreatitis

目的比较高脂血症性急性胰腺炎(hyperlipidemic acute pancreatitis,HLAP)与胆源性急性胰腺炎(biliary acute pancreatitis,BAP)患者的血脂、血淀粉酶(amylase,AMY)和尿淀粉酶(urine amylase,UAMY)含量水平。方法选取2014年8月-2016年8月在成都军区机关医院就诊的急性胰腺炎(acute pancreatitis,AP)患者218例,其中HLAP患者117例,BAP患者101例,分析两组患者血脂、AMY、UAMY、血葡萄糖(Glu)、乳酸脱氢酶(LDH)、血红细胞压积(HCT)、C反应蛋白(CRP)、治疗及预后的情况。结果HLAP组的甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白(HDL-C)、低密度脂蛋白(LDH-C)、平均载脂蛋白A(Apo-A)和平均载脂蛋白B(Apo-B)含量水平均高于BAP组,两组之间比较,差异有统计学意义(P<0.05)。HLAP组的AMY、UAMY和LDH含量水平低于BAP组,HLAP组的Glu、HCT和CRP含量水平高于BAP组,两组之间比较,差异有显著统计学意义(P<0.01)。HLAP组的复发、手术治疗和病死例数高于BAP组,两组之间比较,差异有统计学意义(P<0.05)。结论 HLAP患者的糖脂质含量水平高于BAP患者,AMY和UAMY含量水平低于BAP患者。

Objective To compare the levels of glycolipid,amylase（AMY）and urine amylase（UAMY）in hyperlipidemic acute pancreatitis（HLAP）and biliary acute pancreatitis（BAP）patients.Methods Two hundred and eighteen cases of acute pancreatitis（AP）patients were selected in the Institution Hospital of Chengdu Military Command from Aug.2014 to Aug.2016,and divided into HLAP group（n=117）and BAP group（n=101）.The blood lipid,serum amylase（AMY）,urine amylase（UAMY）,blood glucose（Glu）,lactate dehydrogenase（LDH）,blood hematocrit（HCT）,C reactive protein（CRP）of patients with treatment and prognosis between two groups were analyzed.Results The levels of TG,TC,HDL-C,LDH-C,Apo-A and Apo-B in the HLAP group were higher than those in BAP group,and there was statistical difference between two groups（P〈0.05）.The levels of AMY,UAMY and LDH in the HLAP group were lower than those in BAP group,the levels of Glu,HCT and CRP in the HLAP group were higher than those in BAP group,and there was significant difference between two groups（P〈0.01）.Recurrence,surgical treatment and death cases of HLAP group were higher than those in BAP group,there was statistical difference between two groups（P〈0.05）.Conclusion The level of serum lipid in HLAP patients is higher than the patients with BAP,the levels of AMY and UAMY in HLAP patients are lower than the patients with BAP.