402例广州市耐多药结核病患者人口学特征分析

Demographic Characteristics of 402 Cases with Multi-drug resistant Tuberculosis Patients in Guangzhou

目的通过耐多药结核病患者人口特征分析,初步探索本市耐用多药结核病流行规律。方法依托本院广东地区结核病生物样本库信息资料系统,对2009—2015年来就诊且相关资料齐备的402例耐多药结核病患者进行回顾性分析,从患者性别构成、户籍类别、居住地域分布、年龄结构等方面探讨其人口学特点。结果在402例耐多药结核患者中,男、女性别比为2.12。其中:广州市户籍人口患者占56.96%(229/402)、广东省内流动人口患者占15.92%(64/402)、广东省外流动人口患者占27.11%(109/402);中心城区人口和城市郊区人口患者分别占56.72%(228/402)和43.28%(174/402);少年(<15岁)、青年(15~44岁)、中年(45~64岁)、老年(≥65岁)年龄别患者分别占0.25%(1/402)、57.96%(233/402)、30.85%(124/402)、10.95%(44/402)。结论广州市耐多药结核病流行具有以中青年为主、在人口稠密的城市中心区居住与流动人口所占例大等人口学特点,预示其控制难度大,必须高度关注并采取强力措施以遏制耐多药结核病的蔓延。

Objective To study the epidemic situation of multi - drug resistant tuberculosis （ MDR - TB） in Guang-zhou by analyzing the demographic characteristics of cases with multi - drug resistant tuberculosis from Guangzhou. Methods Based on the information system of bio - bank of tuberculosis in our hospital, 402 cases with MDR - TB who saw doctors during 2009 -2015 and whose information was complete were analyzed. The analysis content included gender composition, census register, age structure. Results The ratio male to female was 2. 12 among them. The cases of census register in Guangzhou, floating population from Guangdong and from other provinces accounted for 56. 96% （229/402） , 15.92% （64/ 402） and 27. 11% （109/402） respectively. Fifty - six point seven two percent of these cases lived in downtown Guangzhou and the rest of 43.28% （174/402） lived in suburbs of Guangzhou. As to age structure, juvenile （ 〈 15 years old） , youth （15 -44 years） , middle age （45 -64 years old） and old age （ ^65 years old） accounted for 0. 25% （1/402） , 57. 96% （233/402） , 30.85% （124/402） and 10.95% （44/402） respectively. Conclusion It is the demographic characteristics of MDR - TB epidemic in Guangzhou that cases of young and middle - age are great majority and cases lived in populous downtown and floating population account for a high proportion. These demographic characteristics indicate that MDR - TB control is very difficult in Guangzhou. Thus, it is essential to give high attention and take strong measures for curbing MDR - TB.