穴位注射结合伐昔洛韦、匹多莫德治疗复发性生殖器疱疹疗效观察

Efficacy of acupoint injection combined with Valacyclovir and Pimodomide in the treatment of recurrent genital herpes

目的:探讨穴位注射结合伐昔洛韦、匹多莫德治疗复发性生殖器疱疹的临床效果。方法:选择88例复发性生殖器疱疹患者作为研究对象,根据治疗方法不同分为两组,对照组给予伐昔洛韦+匹多莫德治疗,观察组给予穴位注射结合伐昔洛韦、匹多莫德治疗,并对治疗效果进行比较。结果:观察组临床总有效率为81.8%,对照组为75.0%,两组总有效率比较差异有统计学意义(P<0.05),观察组临床疗效高于对照组;观察组患者治疗后自觉症状消失时间、结痂时间、皮损愈合时间明显少于对照组,治疗6个月后复发次数明显少于对照组,两组比较差异有统计学意义(P<0.05)。结论:应用穴位注射结合伐昔洛韦、匹多莫德对复发性生殖器疱疹进行治疗临床效果显著,复发率低,具有更高安全性。

Objective：To investigate the clinical effect of acupoint injection combined with Valacyclovir and Pimodomide in the treatment of recurrent genital herpes. Methods： 88 patients with recurrent genital herpes were enrolled in this study. The patients were divided into two groups according to the treatment method.The control group was given Valacyclovir ＋ Pimodomide treatment,the observation group given acupoint injection combined with Valacyclovir,Pimodomide treatment,and the treatment effect were compared.Results： The total effective rate was 81.8% in the observation group and 75.0% in the control group. The total effective rate of the two groups was significantly different（P〈0. 05）. The clinical efficacy of the observation group was higher than that of the control group. The time of symptoms disappear,crust and skin recover was significantly shorter than that of control group. The time of recurrence was significantly lower than that of the control group after 6 month treatment with stastical difference（P〈0.05）. Conclusion：Acupoint injection combined with Valacyclovir and Pidotimod for the treatment of recurrent genital herpes has a more significant clinical effect and a lower recurrence rate,with higher safety.