关于规范界定有毒中药毒性的若干建议

Some Suggestions on Standardizing the Toxicity of Toxic Traditional Chinese Medicine

目的探讨新版药典对界定有毒中药的毒性大小、毒性成分、有效成分、用法用量等存在的突出问题,分析存在的问题对临床应用的影响,并针对存在的突出问题,提出若干建议。方法实证分析新版药典界定有毒中药的毒性大小、有效成分、毒性成分、用法用量等方面存在的突出问题。结果有毒中药的毒性大小、有效成分、毒性成分、用法用量缺乏客观的理论数据,无统一标准。结论应加强对有毒中药的药理学、毒理学研究,科学测定有毒中药的生品及炮制品的毒性大小、有效成分、毒性成分,规范其用法用量。

Objective To explore the existing problems of new pharmacopoeia in defining the toxicity degree, toxic ingredients, active ingredients, usage and dosage of toxic traditional Chinese medicine, analyze the influence of the existing problems on clinical application, and put forward some suggestions. Methods The existing problems of new pharmacopoeia in defining the toxicity degree, active ingredients ,toxic ingredients, usage and dosage of Chinese traditional medicine were analyzed by demonstration. Results The toxic traditional Chinese medicine＇ s toxicity, active ingredients, toxic ingredients, usage and dosage are lack of objective theory data and there is no untied standard. Conclusion It is necessary to strengthen the study on toxic traditional Chinese medicine pharmacology and toxicology, scientifically determine the toxicity degree, active ingredients and toxic ingredients of the toxic traditional Chinese medicines of raw products and processed products, and standardize the usage and dosage.