球形活性炭对DL-β-氨基异丁酸吸附性能研究

Adsorption of spherical activated carbon against DL-β-aminobutyric acid

考察自制聚苯乙烯基球形活性炭(PACSS)对尿毒症毒素DL-β-氨基异丁酸(DL-β-AIBA)的吸附性能,以探究其治疗慢性肾病的可能性。测定了4种活性炭对DL-β-AIBA的吸附等温线、吸附动力学曲线及3 h内吸附率。结果表明,DL-β-AIBA在球形活性碳上的吸附行为符合Freundlich吸附等温线,平衡吸附量与比表面积无关,而与孔径范围在0.6~0.8 nm的超微孔容积有较好的线性关系。动力学符合拟二级动力学模型,颗粒内扩散不是唯一的控速步骤。3 h内,4种活性炭对DL-β-AIBA的吸附率可达40%以上(最高52%),是相同条件下商品药用炭的2.3~3倍,表明其在短时间内对DL-β-AIBA具有较强的吸附能力。

The ability of self-prepared polystyrene-based spherical activated carbons（ PACSS） to remove DL-β-aminobutyric acid（ DL-β-AIBA）,a kind of uremic toxin,is investigated to explore possibility of curing chronic renal disease.The adsorption equilibrium,adsorption kinetic curves and 3 h adsorption rates of 4 kinds of activated carbons for DL-β-AIBA are measured.Results reveal that the adsorption action of DL-β-AIBA on PACSSfits Freundlich adsorption isotherm well.The equilibrium adsorption amount of DL-β-AIBA is independent on specific surface area,but has a good linear relationship with the micro pore volume of pore diameter between 0. 6-0. 8 nm.The adsorption kinetics is found to comply with the pseudo-second-order equation,and the internal diffusion is not the only rate-controlling step. Within 3hours,adsorption rates of four kinds of activated carbons against DL-β-AIBA are all higher than 40%（ up to 52%）,which is 2. 3-3 times that of medical charcoal under the same conditions,illustrating that the spherical activated carbon has a good adsorption capacity for DL-β-AIBA.