原发性肝癌的早期筛查及诊断

Advances in early screening and diagnosis of hepatocellular carcinoma

肝癌是我国死亡率位居第二的恶性肿瘤,每年死亡人数占全球肝癌死亡病例数的51%,给我国的社会和医疗带来了沉重的负担。早期诊断是预防肝癌、提高肝癌患者生存率最重要的措施之一,开发应用简单、方便、快捷的诊断方法是目前研究的努力方向。肝癌早期诊断的主要方法包括:影像学诊断、蛋白标志物检测、分子标志物检测等途径,其中AFP对肝癌的早期诊断有重要价值,AFP家庭自测的开展普及可实现患者的AFP定期监测,助力肝癌早诊,开创肝癌早筛早诊的新途径。

Hepatocellular carcinoma（HCC） is a malignant tumor with the second highest mortality rate in China,and annual deaths account for 51% of all deaths in the world.HCC brings heavy burdens to the society and medical care in China.Early diagnosis is one of the most important methods for preventing HCC and improving survival rate of HCC patients,and the development of simple,convenient,and quick diagnostic methods is a direction for current research.Methods for the early diagnosis of HCC mainly include imaging diagnosis and measurements of protein markers and molecular markers.Alpha-fetoprotein（AFP） has an important value in the early diagnosis of HCC.One Step AFP test helps the patients to measure AFP at home by themselves and realize the regular monitoring of AFP level,which supports the early diagnosis of HCC and creates a new approach for early screening and diagnosis of HCC.