雾化吸入激素治疗老年急性加重期支气管哮喘患者的临床效果观察

Observation on the Clinical Effect of Aerosol Inhalation with Hormone in the Treatment of Acute Exacerbation of Bronchial Asthma in Elderly Patients

目的观察雾化吸入激素治疗老年急性加重期支气管哮喘患者的临床效果。方法选择我院2014年5月至2016年5月期间收治的90例老年急性加重期支气管哮喘患者,根据患者个人意愿分为布地奈德(BUD)组和泼尼松(PRED)组,每组45例。BUD组患者定量雾化吸入BUD,PRED组每天口服30毫克PRED。比较两组患者治疗后的肺功能指标(FEV1、PEF)和临床评分。结果治疗7天后,BUD组的临床评分显著高于PRED组,FEV1显著高于PRED组,PEF显著低于PRED组,差异均有统计学意义(P<0.05)。结论雾化吸入激素治疗老年急性加重期支气管哮喘患者的临床疗效显著优于口服泼尼松,能够有效改善患者的病情和肺功能,值得临床推广应用。

Objective To observe the clinical effect of aerosol inhalation with hormone in the treatment of acute exacerbation of bronchial asthma in elderly patients. Methods 90 cases of elderly patients with acute exacerbation of bronchial asthma admitted to our hospital from May 2014 to May 2016 were selected. ACcording to patients＇ willing, all cases were divided into the BUD group and the PRED group, with 45 cases in each group. Patients in the BUD group received budesonide （BUD） by aerosol inhalation, while patients in the PRED group received 30 mg prednisone by oral administration. After treatment, the pulmonary fimction indicators （FEVt and PEF） and clinical score were compared between two groups. Results After 7. days＇ treatment, the clinical score of BUD group was significantly higher than that of PRED group, FEVt was significantly higher than that of PRED group, and the PEF was significantly lower than that of PRED group, with statistical differences （P〈0.05）. Conclusions Hormone by aerosol inhalation has better clinical curative effect than prednisone by oral administration in the treatment of elderly patients with acute exacerbation of bronchial asthma, which can effectively improve patients＇ disease condition and pulmonary function, and is worthy of clinical promotion and application.