重度异型增生IPMN的CT影像特征研究

A retrospective study on CT imaging features of severe hyperplasia of intraductal papillary mucinous neoplasms

目的:探讨胰腺导管内乳头状黏液性肿瘤(IPMN)的CT影像特征,重点研究重度异性增生IPMN的CT特征。资料与方法:本研究搜集并回顾分析了39例IPMN患者的临床资料、病理资料及CT影像表现,运用统计学方法分析重度异型增生IPMN与轻-中度异型增生IPMN患者及浸润性癌患者的CT影像学差异。结果 :重度异型增生IPMNs的CT影像表现部分与浸润性癌类似,提示有一定的恶性倾向(囊壁增厚、壁内结节、囊壁及结节强化);部分与轻-中度异型增生IPMN类似,提示有一定的良性倾向(较少出现胰腺周围渗出及淋巴结肿大)。结论:重度异型增生IPMN的CT表现介于轻-中度异型增生IPMN及浸润性癌两组间,具有一定特征。因其特殊的影像特征,临床上对于重度异性IPMN更需引起足够重视。

Objective： To explore CT imaging features of severe dysplasia of pancreatic intraductal papillary mucinous neoplasms（IPMN）. Materials and Methods： As a retrospective study, the clinical, pathological and CT imaging data of 39 IPMN patients were collected and analyzed. CT imaging features of severe dysplasia were compared with slight to moderate dysplasia and invasive carcinoma. Results： CT features of severe dysplasia IPMN was partly similar with invasive carcinoma, suggesting it has a certain malignant tendency（cystic wall thickening, wall nodule, cystic wall and nodular enhancement）. Meanwhile, it was partly similar to slight to moderate dysplasia IPMN, suggesting it has a certain benign tendency（less frequent occurence of peripancreatic haziness and enlarged lymph nodes）. Conclusion： Severe dysplasia IPMN have certain CT imaging characteristics between those of slight to moderate dysplasia and invasive carcinoma. Therefore, more attention needed for severe dysplasia IPMN in clinics.