条件性关联记忆消退的研究进展

The research progress of conditional associative memory extinction

条件性关联学习是人类以及动物学习记忆的一种重要形式,将条件刺激和非条件刺激在时间和空间上关联后,中枢神经系统在相关机制下对原始信息进行加工处理后储存在脑内。条件性关联学习的消退则是对已形成的关联条件反射的抑制或削弱,其机制的研究在神经生物科学和医学临床上具有重要价值。笔者回顾近年来国内外的相关研究,从目前消退涉及的主要概念和机制进行阐述和分析,为以后学者们在学习记忆等方向的研究提供理论依据和实验经验。

Conditional associative memory is an important form of human and animal learning and memory.When the conditioned and unconditioned stimuli are correlated in time and space,the central nervous system processes the original information and stores it in the brain with the relevant mechanism.The extinction of conditional associative memory is the suppression of the formed conditional reflex.The study of its mechanism is of great value in neurobiology and clinical medicine.This article reviewed recent research at home and abroad,and analyzed the main mechanisms involved in the memory extinction,provided theoretical basis and experimental experience for the future study of learning and memory.