摘要
目的建立适用于重庆地区儿童的降钙素原(PCT)生物参考区间。方法招募120例健康儿童,男73例、女47例,年龄0~16岁,采用深圳新产业生物医学工程股份有限公司Maglumi2000plus型电化学发光法PCT检测系统及配套试剂盒检测血清PCT浓度。按照美国临床和实验室标准化协会EP28-A3c文件所规定的方法,分析并确定PCT生物参考区间。结果重庆地区健康儿童血清PCT水平呈偏态分布,不同性别、年龄儿童PCT水平比较差异无统计学意义(P>0.05);儿童PCT生物参考区间为PCT≤0.038μg/L。结论实验室应根据自有检测系统建立适合的生物参考区间。儿童作为特殊人群,更应单独建立相应的生物参考区间。
Objective To establish the biological reference interval of procalcitonin(PCT)applicable for children in Chongqing.Methods Serum PCT level were detected in 120 healthy children with age from 0 to 16 years,including 73 cases of male and 47 cases of female children,by using by Maglumi 2000 plus PCT analysis system.All data was evaluated according to EP28-A3 c document to establish the biological reference interval.Results Data of PCT levels were with non-normal distribution,and without statistical difference between children of different ages and genders(P〉0.05).The biological reference interval of PCT was less than or equal to 0.038μg/L.Conclusion It might be important to establish a usefully biological reference interval in different laboratories with relative detection system,especially for children.
出处
《国际检验医学杂志》
CAS
2017年第14期1935-1936,1939,共3页
International Journal of Laboratory Medicine
关键词
降钙素原
生物参考区间
儿童
procalcitonin
biological reference interval
children