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ERCC1基因表达量及多态性对卵巢癌化疗结局的影响现状 被引量:4

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摘要 卵巢癌铂类耐药及预后不良是世界性难题,严重影响妇女的身体健康。为了提高化疗药物的敏感性和患者的依从性,临床上急需一种预测化疗敏感性和预后的方法,基因多态性因此应运而生。本文将对DNA修复途径上的关键基因ERCC1的表达量及其多态性是否会影响卵巢癌耐药及预后进行综述。
作者 邓茜韩 李力
出处 《现代妇产科进展》 CSCD 北大核心 2017年第6期474-477,共4页 Progress in Obstetrics and Gynecology
基金 广西自然科学基金(No:2014jj AA40673) 广西科学研究与技术开发计划(No:桂科攻14124004)
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