摘要
目的:研究麦冬多糖提取时的变化规律。方法:将麦冬药材粉末经水提醇沉后得到的麦冬多糖作为研究对象,适量水溶解后,模拟麦冬提取工艺,通过测定提取过程中分子量分布值、总糖含量、单糖含量的变化,从而得出麦冬多糖按提取工艺提取时的降解规律。结果:发现麦冬多糖在提取时发生了降解,产生了分子量更小的糖。结论:得到的麦冬多糖变化规律,可用于指导生产中麦冬药材的提取,进而稳定麦冬药材的收率,提高生产效益。
Objective:To study the degradation of Ophiopogon polysaccharide in extraction process.Methods:The Radix Ophiopogonis polysaccharide obtained by water extraction and ethanol precipitation later was used as the object of the study.After appropriate amount of water was dissolved,ascertain by measuring the molecular weight,total sugar content in the extraction process.So the degradation of Radix Ophiopogonis polysaccharide in extraction process was studied.Results:Radix Ophiopogonis polysaccharide degradation in the extraction occurred,resulting in a smaller molecular weight saccharides.Conclusion:This degradation of Ophiopogon polysaccharide in extraction process can guide the production of Radix Ophiopogonis extraction process,so as to stabilize the yield of Ophiopogon japonicus,improve production efficiency.
作者
张璐欣
周学谦
李德坤
周大铮
杨悦武
余伯阳
鞠爱春
ZHANG Luxin ZHOU xueqian LI Dekun ZHOU Dazheng YANG Yuewu YU Boyang JU Aibhun(China Pharmaceutical University, Nanjin 211198, China Tianjin Key Laboratory of Safety Evaluation Enterprise of TCM Injections, Tianjin 300402, China Tianjin Tasly Pride Pharmaceutical Co. , Ltd. , Tianjin 300402, China)
出处
《中国现代中药》
CAS
2017年第7期1007-1011,共5页
Modern Chinese Medicine
关键词
麦冬多糖
提取工艺
糖含量
降解规律
Radix Ophiopogonis polysaccharide
extraction process
sugar content
degradation