穴位贴敷合止嗽散加减治疗感冒后咳嗽的疗效观察

Observation of the Therapeutic Effects on Cough after Common Cold Treated with Acupoint Application and Modified Zhisou Powder

目的观察穴位贴敷合止嗽散加减治疗感冒后咳嗽的疗效。方法将120例感冒后咳嗽的患者随机分成3组,复方右美沙芬止嗽糖浆治疗组(简称右美沙芬组)、止嗽散治疗组(简称止嗽散组)、穴位贴敷合止嗽散治疗组(简称穴位贴敷合止嗽散组),每组40例。结果治疗后右美沙芬组总有效率60%,止嗽散组总有效率67.5%,穴位贴敷合止嗽散组总有效率87.5%,3组疗效比较,差异有统计学意义(χ~2=7.96,P<0.05);右美沙芬组与止嗽散组疗效比较,差异无统计学意义(χ~2=0.49,P>0.25);止嗽散组与穴位贴敷合止嗽散组比较,差异有统计学意义(χ~2=4.59,P<0.05),右美沙芬组与穴位贴敷合止嗽散组疗效比较,差异有统计学意义(χ~2=7.81,P<0.01)。3组不良反应总发生率分别是60.0%、5.0%、7.5%,差异有统计学意义(χ~2=42.11,P<0.05)。结论止嗽散加减治疗感冒后咳嗽与右美沙芬治疗疗效相当。穴位贴敷合止嗽散加减治疗感冒后咳嗽疗效显著优于右美沙芬治疗与止嗽散加减治疗。止嗽散加减治疗与穴位贴敷合止嗽散加减治疗的总不良反应发生显著少于右美沙芬治疗。

Objective To observe the therapeutic effects on cough after common cold treated with acupoint application and modified Zhisou powder. Methods One hundred and twenty patients of cough after common cold were randomized into three groups,No. 1 treatment group,treated with compound dextromethorphan syrup; No. 2 treatment group,treated with zhisou powder; No. 3 treatment group,treated with the combined therapy of acupoint application and zhisou powder,40 cases in each one. Results After treatment,the total effective rate was 60% in the No. 1 treatment group,was 67. 5% in the No. 2 treatment group and was87. 5% in the No. 3 treatment group,indicating the significant differences among the three groups（ χ~2=7. 96,P〈0. 05）. The difference was not significant between the No. 1 treatment group and the No. 2 treatment group（ χ~2= 0. 49,P〈0. 25）. The difference was significant between the No. 2 treatment group and the No. 3 treatment group（ χ~2= 4. 59,P〈0. 05）,and between the No. 1 treatment group and the No. 3 treatment group（ χ~2= 7. 81,P〈0. 01）. The total incidences of adverse reactions were 60. 0%,5. 0% and 7. 5% in the three groups separately,indicating the significant differences（ χ~2= 42. 11,P〈0. 05）. Conclusion The modified Zhisou powder achieves the similar therapeutic effects on cough after common cold as compared with dextromethorphan. The combined therapy of acupoint application and modified Zhisou powder achieves the significant effects as compared with either dextromethorphan or modified Zhisou powder. The incidence of total adverse reactions of the modified Zhisou powder and the combined therapy of acupoint application and modified zhisou powder are lower significantly than dextromethorphan.