摘要
在药理成分或者不同剂量的药物以及新配方对细胞进行可行性分析时,由于低速成像和细胞培养时间的差异所带来的误差是不可避免的。为了获得更加精确的结果,我们提出了分布式原子力显微系统,把两个原子力显微镜集成到一个操作系统中,研究人员可以在一个操作界面上对两个原子力显微镜同时操作。通过这种方式,有望实现对同一时刻不同细胞在相同生长环境,相同细胞在同一时刻不同生长环境以及不同细胞在同一时刻同一生长环境下生长状态的分析。因此,获取样品的效率可以显著提高。
As for the analysis of pharmacological composition or different dose of drugs and the feasibility of new formula to cells, the errors caused by low-speed imaging and the duration of cell culture are inevitable. To get accurate results, a distributed atomic force microscope system was developed. By integrating two atomic force microscopes (AFMs) into one operation system, researchers can manipulate the two AFMs in one user interface at the same time. By using this method, the growth states of different cells in the same environmenl condition at the same time, same cells in differen! environment condition at the same time, and different cells in the same environment condition at different times can be analyzed intuitively; Furthermore, the efficiency of sample imaging will be improved clearly.
作者
曾俊智
宋正勋
曲英敏
王作斌
Zeng Junzhi Song Zhengxun Qu Yingmin(Changchun University of Science and Technology, Changchun, 130022)
出处
《生命科学仪器》
2017年第3期45-49,共5页
Life Science Instruments
基金
欧盟第七研究框架计划EU FP7(BIORA No.612641)
国家(中德)国际合作研究计划(No.2012DFA11070)
吉林省国际科技发展计划(No.20140414009GH)
关键词
原子力显微镜
分布式控制
成像
生物样品
Atomic force microscope
Distributed control
hnaging
Biological sample