上海市松江区呼吸系统疾病死亡与三种大气污染物的关联性

Association between respiratory diseases mortality and ambient air pollution in Songjiang District of Shanghai

目的探究大气污染物PM_(10)、SO_2、NO_2与呼吸系统疾病死亡的关联性。方法汇总上海市松江区2011—2012年大气污染数据,并收集户籍人口呼吸系统死亡的全部病例,采用时间分层-病例交叉设计方法分析两者间关系,并对不同年龄别、性别人群的超额死亡风险进行分析。结果 SO_2、NO_2与呼吸系统疾病死亡相关,当NO_2浓度每增加10μg/m^3时,在lag0时间点上导致呼吸系统死亡发生率明显提高[OR=1.061(1.000,1.126)];与女性相比,NO_2明显增加了男性呼吸系统疾病死亡风险[OR=1.109(1.031,1.194)]。结论大气污染可增加人群呼吸系统疾病死亡的风险,对男性尤甚。

Objective To investigate the association between atmospheric pollutants as PM10, SO2 , NO2 and respiratory diseases mortality. Methods By summarizing air pollution data from 2011 to 2012 in Songjiang District of Shanghai and collecting all death cases of respiratory system, was adopted the time -stratified case crossover approach for analysis on the relationship between air pollution and respiratory mortality. And the excess risk of death was also analyzed in groups of different age and sex. Results Respiratory mortality was found to be significantly associated with air pollutants as SO2 and NO2. The OR of respiratory mortality for NO2 is 1. 061 （ 1. 000, 1. 126 ） at the time point of LagO for every 10 μg/m3 increase. For an increase of 10 μg/m3 for NO2, OR of respiratory mortality for male was 1. 109 （ 1. 031, 1. 194） at the time point of LagO, which was substantially higher than that for female. Conclusion This study provides new evidence for the association between exposure to ambient air pollution and respiratory mortality. Our results also suggest that males may face more risks than females in respiratory mortality in relation to NO2 exposure.