期刊文献+

Research progress in the effect of cytokines on myocardial fibrosis

Research progress in the effect of cytokines on myocardial fibrosis
原文传递
导出
摘要 Background Myocardial fibrosis is one process of the various heart diseases, which leads to common pathological changes when it develops to a certain stage. It is the main cause of ventricular remodeling which eventually leads to different degrees of cardiac dysfunction, malignant arrhythmias and sudden cardiac death. Many studies have shown that various cytokines play a very important role in the development of myocardial fibrosis. This paper reviews the latest researches on the role of cytokines in myocardial fibrosis. Background Myocardial fibrosis is one process of the various heart diseases, which leads to common pathological changes when it develops to a certain stage. It is the main cause of ventricular remodeling which eventually leads to different degrees of cardiac dysfunction, malignant arrhythmias and sudden cardiac death. Many studies have shown that various cytokines play a very important role in the development of myocardial fibrosis. This paper reviews the latest researches on the role of cytokines in myocardial fibrosis.
出处 《South China Journal of Cardiology》 CAS 2017年第2期160-166,共7页 岭南心血管病杂志(英文版)
关键词 myocardial fibrosis CYTOKINES myocardial fibrosis cytokines
  • 相关文献

参考文献4

二级参考文献46

  • 1熊兰英.浅谈石蜡制片——HE染色点滴体会[J].检验医学与临床,2006,3(4):169-169. 被引量:5
  • 2刘勇,钱孝贤,吴伟康,周彬,陈璘,刘金来.四逆汤对兔髂动脉球囊损伤病变区TGF-β_1表达的影响[J].中国病理生理杂志,2006,22(11):2151-2155. 被引量:7
  • 3Pfeffer M A,Braunwald E.Ventricular remodeling after myocar-dial infarction.Experimental observations and clinical implica-tions[J].Circulation,1990,81:1161.
  • 4Thum T,Gross C,Fiedler J,et al.MicroRNA-21 contributes tomyocardial disease by stimulating MAP kinase signalling in fibro-blasts[J].Nature,2008,456(7224):980.
  • 5Teekakirikul P,Eminaga S,Toka O,et al.Cardiac fibrosis inmice with hypertrophic cardiomyopathy is mediated by non-myo-cyte proliferation and requires Tgf-β[J].J Clin Invest,2010,120(10):3520.
  • 6Wang J,Xu N,Feng X H,et al.Targeted disruption of Smad4in cardiomycytes results in cardiac hypertrophy and heart failure[J].Circ Res,2005,97(8):821.
  • 7Yuan S M,Jing H.Cardiac pathologies in relation to Smad-de-pendent pathways[J].Interact Cardiovasc Thorac Surg,2010,11(4):455.
  • 8JESSUP M, BROZENA S. Heart failure[J]. N Engl J Med,2003,348 : 2007- 2018.
  • 9DANIELS A, VAN BILSEN M, GOLDSCHMED ING R, et al. Connective tissue growth factor and Physiol, 2009, 195:321.
  • 10KOITABASHI N, ARAI M, NIWANO K, et al. Plasma connective tissue growth factor is a novel po- tential biomarker of cardiac dysfunction in patients with chronic heart failure[J]. Eur J Heart Fail,2008, 10:373-379.

共引文献40

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部