缺血性脑卒中复发与睡眠时长的相关性研究

Research on the relationship of recurrence of cerebral infarction with total sleeping time

目的缺血性脑卒中是威胁人类健康的重要疾病,卒中复发更易造成患者致残及死亡。为明确缺血性脑卒中的复发原因,文中探讨夜间睡眠时长对于缺血性卒中复发的影响。方法回顾性分析2016年3月至2016年10月期间在天津医科大学总医院住院治疗的缺血性脑卒中患者70例,并按照病史分为首发组及复发组。分析入组对象行多导睡眠监测(PSG)结果资料;选取同期20名门诊患者进行PSG监测并作为对照。记录所有研究对象睡眠总时长(TST)、性别及年龄。将年龄、性别、TST作为自变量,缺血性卒中复发作为因变量,进行Logistic多元回归分析。结果复发组TST[(5.59±1.62)h]分别短于初发组[(6.56±0.99)h]及对照组[(7.19±0.61)h],且初发组TST时长短于对照组,差异均有统计学意义(P<0.05)。Logistic多元回归分析发现睡眠总时长是缺血性脑卒中复发的独立危险因素;且随着TST的减少,缺血性脑卒中复发的风险越大。结论睡眠时间缩短可能会导致缺血性卒中复发风险增加,需引起临床医师的关注。

Objective Cerebral infarction is a main disease threatening human health and the recurrence of cerebral infarction is more inclined to cause disability and death. The article aimed to explore the influence of total sleeping time on the recurrence of cerebral infarction. Methods According to the criteria,70 cases of cerebral infarction patients who hospitalized in our hospital from March 2016 to November 2016 were selected to undergo polysomnography（ PSG） and were divided into two groups according to medical history： original group and recurrence group. Another 20 simultaneous outpatients who had no significant diseases to undergo PSG were chosen as the control group. Data were collected on all the individual＇s total sleeping time（ TST）,gender and age. Hypothesis testing and logistic related analysis were applied in data analysis. Results The TST of recurrence group was shorter than those of the original group and the control group（ P〈0.05）,among which the TST of the original group is shorter than that of the control group（ P〈0.05）,both representing significant difference. Multiple regression analysis showed that TST was an independent risk factor for the recurrence of cerebral infarction and that the risk of recurrence of cerebral infarction increased with the lack of TST. Conclusion The shortening of TST may increase the risk of the recurrence of cerebral infarction.