摘要
糖尿病是重型地中海贫血(TM)患者铁超载的重要并发症之一。对1例TM患者在胰岛素基础上联合强化排铁治疗。随着铁蛋白的快速下降,患者胰岛素敏感性增加,胰岛素分泌功能改善,胰岛素用量逐步减少并最终停止使用。TM患者需监测其胰岛功能,强化排铁有望治愈早期发现的糖尿病。
Diabetes mellitus is an important complication secondary to iron overload in patients with thalassemia major. One case was treated with insulin and intensified iron chelation therapy. During treatment,together with the rapidly decreasing of serum ferritin level,insulin sensitivity was increased and insulin secretion function was improved in this patient,therefore insulin dosage was decreased and finally halted. Function of pancreas should be monitored in patients with thalassemia major. Early extensive iron chelation therapy may stop the development of diabetes mellitus.
出处
《中国糖尿病杂志》
CAS
CSCD
北大核心
2017年第7期659-661,共3页
Chinese Journal of Diabetes
基金
广西自然科学基金(2014GXNSFBA118187
2015GXNSFAA139164)
关键词
重型地中海贫血
铁超载
糖尿病
去铁治疗
胰岛素
Thalassemia major
Iron overload
Diabetes mellitus
Iron chelation therapy
Insulin