2型糖尿病及合并并发症患者主要生化指标分析

Analysis on main biochemical indexes in patients with type 2 diabetes mellitus and complications

目的分析2型糖尿病(T2DM)及合并并发症患者的主要生化指标。方法选取2015年3月至2016年3月自贡市第三人民医院收治的T2DM患者112例,根据是否有并发症将其分为T2DM无并发症组(61例)与T2DM合并并发症组(51例),另选取同期体检健康志愿者55例作为对照组。比较各组间胰岛素、空腹血糖(FBG)、D-二聚体(D-D)及血脂[高密度脂蛋白(HDL)、低密度脂蛋白(LDL)、总胆固醇(TC)、三酰甘油(TG)]水平。结果T2DM无并发症组及T2DM合并并发症组患者FBG、D-D、TC、TG及LDL水平均高于对照组,胰岛素与HDL水平均低于对照组,差异均有统计学意义(P<0.05);且除了HDL,胰岛素、FBG、D-D、LDL、TC和TG水平在T2DM合并并发症组与T2DM无并发症组间比较,差异均有统计学意义(P<0.05)。结论定期监测糖尿病患者的血糖、血脂等生化指标是防治糖尿病及其并发症的重要手段。

Objective To analyze the main biochemical indexes in the patients with type 2 diabetes mellitus （T2DM） and complications. Methods A total of 112 cases of patients with T2DM in the Zigong Municipal Third People＇s Hospital were selected from March 2015 to March 2016 and divided into the T2DM without complications group （61 cases） and T2DM with complications group （51 cases） according to whether having complications. Contemporaneous 55 volunteers undergoing physical examination were selected as the control group. The levels of insulin,fasting blood glucose （FBG） ,D-dimer （D-D） and serum lipids （HDL,LDL,TC and TG） were compared among three groups.Results The levels of FBG,D-D,TC,TG and LDL in the T2DM without complica- tions group and T2DM with complications group were higher than those in the control group,while the levels of insulin and HDL were lower than those in the control group,the differences were statistically significant （P〈0.05） ;moreover,except HDL,the lev- els of insulin,FBG,D-D,LDL,TC and TG had statistical difference between the T2DM with complications group and T2DM with- out complications group （P〈0. 05）. Conclusion Regularly detecting the biochemical indexes of blood glucose and lipids in diabetic patients is＇an important mean to preventing and treating diabetes mellitus and its complications.