早发型子痫前期孕妇血清及尿液中胎盘蛋白13的变化

Changes of Placental Protein 13 in Serum and Urine of Women with Early-onset Preeclampsia

目的:探讨早发型子痫前期(PE)孕妇血清与尿液中的胎盘蛋白13(PP13)的检测结果。方法:根据孕周不同分为早发型子痫前期80例与晚发型子痫前期80例,同时选取正常妊娠孕妇50例作为对照组。结果:子痫前期两组孕妇血清与尿液中的胎盘蛋白13水平均明显高于正常孕妇(P<0.05),早发型子痫前期组孕妇血清与尿液胎盘蛋白13水平明显高于晚发型子痫前期组孕妇(P<0.05)。结论:重度子痫前期孕妇血清与尿液中的胎盘蛋白13水平明显升高,而早发型患者的升高更加明显,胎盘蛋白13可以作为早发型子痫前期预测的重要指标。

Objective： To study the early-onset preeclampsia（ PE） in placenta of pregnant women serum and urine protein 13（ PP13） test results. Methods： 160 pregnant women with preeclampsia were divided into 80 cases of early-onset preeclampsia and 80 cases of late onset preeclampsia according to the gestational age. 50 normal pregnant women were selected as the control group. Results： Serum and urine of pregnant women in preeclampsia placental protein 13 levels of two groups were significantly higher than those of normal pregnant women（ P〈0.05）,early onset preeclampsia placental protein 13 levels in serum and urine was significantly higher than that of late onset preeclampsia（ P〈0.05）. Conclusion： The levels of placental protein13 in serum and urine increased significantly in severe preeclampsia women,and the increase of early onset patients was more obvious. Placental protein 13 could be an important indicator of early onset preeclampsia.