腹膜外卵巢移位术与改良卵巢移位术对宫颈癌患者卵巢功能的影响

Effect of extraperitoneal ovarian transposition and modified ovarian transposition on ovarian function in patients with cervical cancer

目的探讨腹膜外卵巢移位术与改良卵巢移位术对宫颈癌患者卵巢功能的影响。方法选取2010年3月至2015年9月间山东潍坊临朐县人民医院收治的140例宫颈癌患者,采用随机数表法将患者分为观察组和对照组,每组70例。观察组行改良卵巢移位术,对照组行腹膜外卵巢移位术。比较两组患者治疗前后孕酮(P)、卵泡刺激素(FSH)、黄体生成素(LH)及雌二醇(E)含量,并发症发生率及随访24周性生活满意度。结果两组患者治疗前P、FSH、LH及E值比较,差异均无统计学意义(均P>0.05)。两组患者治疗后较治疗前比较P值升高、FSH、LH和E值降低,但差异均无统计学意义(均P>0.05)。两组治疗后P、FSH、LH及E值比较差异无统计学意义(P>0.05)。观察组并发症发生率为10.0%,对照组并发症发生率为21.4%,观察组较对照组相比并发症发生率明显降低,差异有统计学意义(P<0.05)。对照组性生活满意率为81.4%,观察组性生活满意率为91.4%,观察组较对照组比较性生活满意明显提高,差异有统计学意义(P<0.05)。结论腹膜外卵巢移位术与改良式卵巢移位手术治疗宫颈癌都可以有效保留卵巢的功能,改良式卵巢移位术可减少并发症的发生,显著提高患者术后性生活满意度。

Objective To explore and analyze the effect of extraperitoneal ovarian transposition and modified ovarian transposition on ovarian function in patients with cervical cancer. Methods From March 2010 to September 2015, 140 patients with cervical cancer treated at Linqu County People＇s Hospital were selected and randomly divided into an observation group and a control group according to the random number table method with 70 patients in each group. Patients in observation group underwent modified ovarian trans- position and patients in control group underwent extraperitoneal ovarian transposition. Progesterone （P） , follicle-stimulating hormone （FSH） , luteinizing hormone （LH） , content of estradiol （ E）, incidence of complications and sexual satisfaction over the follow-up of 24 weeks were compared between the two groups before and after treatment. Results Before treatment, there was no significant difference in P, FSH, LH, and E values between the two groups （P 〉 0. 05）. After treatment, P level increased and FSH, LH, and E decreased compared with before treatment in both groups but the difference was not statistically significat （P 〉 0. 05）. No difference in P, FSH, LH, and E values was noted between the two groups （P 〉 0. 05）. The incidence of complication was 10. 0% for the observation group, which was significantly lower than 21.4% of the control group （P 〈 0. 05）. Sexual satisfaction was 91.4% for the observation group, which was higher than 81.4% of the control group （P 〈 0. 05）. Conclusion Both extraperitoneal ovarian trans- position and modified ovarian transposition can effectively preserve ovarian function and the latter can reduce postoperative complications as well as improve postoperative sexual satisfaction.