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动态调强与容积调强在老年宫颈癌根治性放疗中的剂量学差异 被引量:2

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摘要 目的探讨旋转容积调强技术(VMAT)与固定野动态调强技术(IMRT)在老年宫颈癌患者根治性放疗中剂量学及危及器官保护的差异。方法选取该肿瘤放疗中心接受根治性放疗的老年宫颈癌患者11例,采集CT影像信息后通过VARIAN计划系统对同一图像进行VMAT计划和IMRT计划,比较两者靶区剂量分布、照射野正常组织受量、危及器官受量、治疗时间及加速器跳数(MU)差异。结果与IMRT计划相比,VMAT计划中的适形度指数(CI)更接近1,均匀性指数(HI)更小,差异有统计学意义(P<0.05)。照射野正常组织低剂量照射中,VMAT计划的V10、V20、V30、V40均低于IMRT计划(均P<0.05)。同时VMAT计划中膀胱的Dmean、V30、V40,小肠的Dmean、V20、V30、V40均低于IMRT计划(均P<0.05)。而在股骨头及直肠保护方面,VMAT计划无明显优势。MU及治疗时间方面,VMAT计划明显缩短。结论 VMAT和IMRT计划均能达到计划要求,但前者具有更优的靶区剂量学分布,同时能更好地保护膀胱和小肠,从而减少相关放疗副反应。VMAT计划的MU及治疗时间明显缩短,更符合实际临床要求。
出处 《中国老年学杂志》 CAS 北大核心 2017年第14期3509-3511,共3页 Chinese Journal of Gerontology
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