血清CRP、PCT的检测在新生儿败血症中的诊断价值研究

Diagnostic value of serum CRP and PCT detection in neonatal septicemia

目的探讨在新生儿败血症中实施血清C反应蛋白(CRP)、降钙素原(PCT)检测的诊断价值。方法选取2016年1~12月本院收治的40例新生儿败血症患儿(败血症组)和40例健康新生儿(正常组)进行研究,对所有患儿均实施血清CRP、PCT检测,统计分析两组新生儿的检测结果及诊断阳性状况。结果败血症组患儿血清CRP及PCT水平与正常组相比明显较高,败血症组患儿CRP、PCT单独检测阳性及联合检测阳性率与正常组相比明显较高;败血症组患儿CRP、PCT联合检测阳性率与CRP、PCT单独检测阳性相比明显较高,败血症组中期患儿PCT阳性率及CRP、PCT联合检测阳性率与早期、恢复期患儿相比明显较高,差异有统计学意义(P<0.05)。结论在新生儿败血症中实施血清CRP、PCT联合诊断效果优良。

Objective To investigate the diagnostic value of serum C-reactive protein （CRP） and procalcitonin （PCT） in neonatal sepsis.Methods 40 patients with neonatal sepsis and 40 healthy newborns （normal group） were enrolled in our hospital from January to December 2016,and serum CRP,PCT test,statistical analysis of two groups of neonatal test results and diagnosis of positive status.were compared.Results The sepsis group serum CRP and PCT levels were significantly higher compared with the normal group,the sepsis group with CRP,PCT detection and combined detection of positive positive rate was significantly higher compared with normal group;CRP ,PCT in children with septicemia group, the positive rate of combined detection with CRP,PCT was significantly higher than single detection of positive phase,he positive rate of children with septicemia group interim PCT CRP and PCT,the positive rate of combined detection and early recovery stage were significantly higher,the difference has statistical significance（P〈0.05）.Conclusion The combination of serum CRP and PCT in neonatal sepsis is excellent.