抗血小板聚集治疗大面积脑梗塞效果分析

Effect analysis of anti-platelet aggregation therapy in patients with large area cerebral infarction

目的 探讨对大面积脑梗塞患者采用抗血小板聚集治疗的临床效果.方法 本研究对象来源于我院脑血管科2015年10至2016年10月收治的大面积脑梗塞患者90例,采用双盲法随机分成两组,其中对照组（n=45）采用常规治疗,观察组（n=45）基于对照组加用抗血小板聚集治疗,比较两组患者的临床疗效.结果 观察组总有效率为88.9%,明显高于对照组的66.7%,差异有统计学意义（P〈0.05）;两组治疗前NIHSS评分及BI指数比较无显著性差异（P〉0.05）,治疗后观察组NIHSS评分明显低于对照组,BI指数明显高于对照组,比较有显著性差异（P〈0.05）.结论 抗血小板聚集治疗大面积脑梗塞临床效果较好,可明显改善患者神经功能缺损及日常生活能力,有推广价值.

Objective To investigate the clinical effect of anti-platelet aggregation therapy in patients with large area cere- bral infarction. Methods From October 2015 to October 2016, 90 cases of patients with large area cerebral infarction in our hospital were divided into two groups, the control group （n=45） was treated with conventional therapy, the observation group （n=45） was given anti-platelet aggregation therapy based on the control group, the clinical efficacy of the two groups were compared. Results The total effective rate was 88.9% of the observation group, which was significantly higher than 66.7% of the control group （P〈0.05）. There was no significant difference in NIHSS scores and BI index between the two groups before treatment （P〉0.05）, The postoperative NIHSS scores of the observation group was significantly lower than that of the control group, and the BI index was significantly higher than that of the control group （P〈0.05）. Conclusion Anti-platelet aggrega- tion therapy in large area of cerebral infarction has a preferable effect, and can significantly improve the patient＇s neurologi- cal deficits and daily living ability, it is value to promote.