3Karceski S, Morrell MJ, Carpenter D. Treatment of epilepsy in adults : expert opinion, 2005. Epilepsy Behav, 2005, 7 Suppl 1 : S1-64.
4French JA, Kanner AM, Bautista J, et al. Efficacy and tolerability of the new antiepileptic drugs I. Treatment of new onset epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology, 2004, 62: 1252-1260.
5Perucca E, Gram L, Avanzini G, et al. Antiepileptic drugs as a cause of worsening seizures. Epilepsia, 1998, 39 : 5-17.
6Kwan P, Brodie MJ. Early identification of refractory epilepsy. N Engl J Med, 2000, 342: 314-319.
7Marson AG, Al-Kharusi AM, Alwaidh M, et al. The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial. Lancet, 2007, 369 : 1016-1026.
8Beghi E, Gatti G, Tonini C, et al. Adjunctive therapy versus ahernative monotherapy in patients with partial epilepsy failing on a single drug: a muhicentre, randomized, pragmatic controlled trial. Epilepsy Res, 2003, 57: 1-13.
9Kwan P, Brodie MJ. Epilepsy after the first drug fails : substitution or add-on? Seizure, 2000, 9: 464468.
10Hauser WA. Seizure disorders: the changes with age. Epilepsia, 1992, 33 Suppl 4: $6-14.
