糖尿病患者血脂水平与慢性微血管并发症相关性分析

Analysis of the correlation between blood lipid level and chronic microvascular complications in diabetic patients

目的探究糖尿病患者血脂控制与慢性微血管并发症的相关性。方法对2013年4月至2014年4月我院收治的100例糖尿病患者的临床资料进行分析,根据有无慢性微血管并发症将上述患者分为两组,有慢性微血管并发症者设置为观察组(48例),无慢性微血管并发症者设置为对照1组(52例),选择同时期来我院体检的50名健康人作为对照组2组,比较三组受检者的血脂水平。结果对照2组的FBG、HbA1c、TC、TG、LDL-C均显著低于对照1组和观察组,HDL-C显著高于对照1组和观察组(P<0.05)。对照1组患者的TC、TG、LDL-C显著低于观察组(P<0.05)。结论糖尿病患者血脂水平升高是引起慢性微血管并发症的危险因素,临床应加强糖尿病患者血脂变化水平检测,这对糖尿病慢性微血管并发症的发生、发展和治疗均有积极的意义。

Objective To explore the correlation between blood lipid level and chronic microvascular complications in diabetic patients. Methods The clinical data of 100 patients with diabetes mellitus from April 2013 to April 2014 in our hospital was analyzed. According to the presence or absence of chronic microvascular complications, the patients were divided into two groups： patients with chronic microvascular complications were included as the observation group（48 cases） and with no chronic microvascular complications were included as the control group 1（52 cases）, and 50 healthy people underwent physical examinations in our hospital in the same period were selected as the control group 2, then the blood lipid levels in the three groups of subjects were compared. Results The levels of FBG, HbA1c, TC, TG and LDL-C in the control group 1 were significantly lower than those in the control group 2 and the observation group, the level of HDL-C was significantly higher than that in the control group and the observation group（P〈0.05）. The levels of TC, TG and LDL-C in the control group 1 were significantly lower than those in the observation group（P〈0.05）. Conclusion Elevated blood lipid levels in diabetic patients are risk factors of chronic microvascular complications, the clinic should strengthen the detection of changes of blood lipid in diabetic patients, which has a positive meaning for the genesis,development and treatment of chronic microvascular complications of diabetes.