胺碘酮治疗心衰合并心律失常的临床效果

Clinical effect of amiodarone in the treatment of heart failure complicated with arrhythmia

目的分析胺碘酮治疗心衰合并心律失常疾病的临床效果。方法随机选取我院收治的72例心衰合并心率失常患者,随机分为对照组和观察组,每组36例。对照组患者采用常规疗法,观察组患者在常规疗法的基础上采用胺碘酮治疗,对比两组患者的心功能和心率失常改善情况,以及治疗前、后的心电图QTC间期和心率变化。结果观察组患者的心功能及心律失常临床总有效率分别为83.33%、77.78%,明显高于对照组的66.67%、66.67%,差异具有统计学意义(P<0.05);治疗后,两组患者的心电图QTC间期和心率均有明显改善,且观察组明显优于对照组,差异具有统计学意义(P<0.05)。结论胺碘酮治疗心衰合并心律失常具有非常好的临床效果,能够有效改善患者的心功能及心律失常症状。

Objective To analyze the clinical effect of amiodarone in the treatment of heart failure complicated with arrhythmia. Methods Seventy-two heart failure complicated with arrhythmia patients admitted in our hospital were selected and ramdomly divided into control group and observation group, with 36 cases in each group. The control group received routine treatment, and the observation group accepted amiodarone on the basis of the control group. The heart function, improvement of arrhythmia, QTC interval of ECG before and after treatment and heart rate of the two groups were com- pared. Results The total effective rates of heart function and improvement of arrhythmia in the observation group were 83.33% and 77.78% respectively, which were higher than 66.67% and 66.67% in the control group （P〈0.05）. After treat- ment, the QTC interval of ECG and heart rate of the two groups improved, and those of the observation group were better than the control group （P〈0.05）. Conclusion Amiodarone in the treatment of heart failure complicated with arrhythmia has significant clinical effect, which can effectively improve the heart function and arrhythmia symptoms of the patients.