胺碘酮治疗急性心肌梗死后室性心律失常的疗效分析

Therapeutic effect analysis of amiodarone on ventricular arrhythmia after acute myocardial infarction

目的观察胺碘酮治疗急性心肌梗死后室性心律失常的临床效果。方法选取我院2015年6月至2016年6月收治的62例急性心肌梗死后室性心律失常患者,根据治疗方法分为对照组和研究组,每组31例。两组患者均行常规治疗,研究组在此基础上行胺碘酮治疗,比较两组患者的临床治疗效果。结果治疗前,两组患者HR及LVEF水平比较,差异无统计学意义(P>0.05);治疗后,两组患者HR及LVEF水平均显著改善,且研究组改善更明显,差异有统计学意义(P<0.05)。治疗后,研究组临床总有效率为90.32%,明显高于对照组的74.19%,差异有统计学意义(P<0.05)。结论应用胺碘酮治疗急性心肌梗死后室性心律失常,有利于改善患者心功能,具有较高的临床应用价值。

Objective To observe the clinical effect of amiodarone on ventricular arrhythmia after acute myocardial infarction. Methods Sixty-two patients with ventricular arrhythmia after acute myocardial infarction admitted in our hospital from June 2015 to June 2016 were divided into control group and study group according to the treatment methods, with 31 cases in each group. Both of groups received routine treatment, while the study group added amiodarone for treatment, then the clinical effects of the two groups were compared. Results Before treatment, there were no significant differ- ences between the levels of HR and LVEF in the two groups （P〉0.05）; after treatment, the levels of HR and LVEF signifi- cantly improved in both groups, and the improvement was more significant in the study group （P〈0.05）. After treatment, the total effective rate of the study group was 90.32%, which was significantly higher than 74.19% of the control group （P〈 0.05）. Conclusion The application of amiodarone in the treatment of ventrieular arrhythmia after acute myocardial infarc- tion is beneficial to the improvement of cardiac function and has high clinical nutritional value.